Saturday 7 January 2012

Transcription and Translation

This is one for those doing AS Biology this week...

The difference between RNA and DNA is that RNA is a single strand, has a ribose sugar opposed to a deoxyribose sugar, and uses the base Uracil as a replacement to Thymine.

-Transcription
This is the process where mRNA (messengerRNA) is formed when the DNA unwinds in a certain section. The strand of DNA is copied via free nucleotides coming together opposite their complementary bases and being stuck together into the mRNA by RNA polymerase. The mRNA then leaves the cell through the nuclear pores and attaches itself to a ribosome. Once it has left the DNA, it winds itself back up into its double helix structure.

-Translation
This process involves tRNA (transferRNA) and ribosome's. The ribosome acts as a holding site for the tRNA and mRNA to come together and for the mRNA to be translated. On the tRNA there is an anticodon. This anticodon is complementary to a codon (triplet base sequence) on the mRNA and the i.e. if the mRNA had a triplet code of UGC the anticodon would be ACG. The tRNA therefore has complementary bases to the mRNA and this is the start of the formation of the amino acid chains.

Attached to the top of the tRNA is a certain amino acid and this amino acid forms a peptide bond with the amino acid on the next tRNA, which has an anticodon that is complementary to the next triplet code. This is how the proteins are formed, where they then form a tertiary (3D) structure to create the final product.

I found a video on YouTube (http://www.youtube.com/watch?v=TfYf_rPWUdY&feature=related that sums it up quite well.

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